Hair loss is a universal concern that impacts individuals across all demographics. Driven by factors like hormonal changes, inflammation, stress, pollution, and genetics, it poses a complex challenge for formulators aiming to deliver effective solutions. 

Today’s consumers demand more than just basic remedies; they are seeking targeted, multi-functional products that align with the growing trends of sustainability and wellness.

The new generation of haircare ingredients from Sinerga fulfil all these demands, leveraging natural extracts and advanced technology to offer multi-functional benefits, from reducing inflammation and balancing the microbiome to stimulating cellular activity. 

Sinerga’s approach to haircare is centred around ‘skinification’, which recognises that there is a critical link between scalp health and hair resilience. Just as healthy skin is the foundation for radiance, a healthy scalp is the key to strong, beautiful hair. 

Ingredients like Tricho-Solve mirror skincare routines, incorporating actives traditionally used for facial care into formulations for the scalp and hair.

What is Tricho-Solve?

INCI – Picea Abies Extract, Cocoyl Proline, Glycerin, Aqua

Tricho-Solve is a natural, biotechnology-derived active ingredient designed to combat the root causes of hair loss: hormonal imbalances and inflammation. Its effectiveness lies in its dual action of inhibiting 5α-reductase and reducing inflammation, while also stimulating follicular activity for visible improvements in hair density and growth.

Ingredient Highlights

Natural Source: Derived from Picea abies extract, rich in lignans and polyphenols known for their antioxidant and anti-inflammatory properties.

Patented Green Technology: Ensures a 76% improvement in bioavailability, maximising efficacy.

Multi-Targeted Action: Combines hormonal regulation, anti-inflammatory effects, and follicle stimulation to address hair loss comprehensively.

Benefits of Tricho-Solve

Inhibits 5α-Reductase: Reduces the production of DHT, a hormone that contributes to androgenic alopecia.

Anti-Inflammatory: Decreases IL-1α release, which is linked to hair follicle damage and conditions like alopecia areata.

Stimulates Protein Synthesis: Enhances keratin production, reinforcing the hair shaft.

Promotes Follicular Health: Boosts cell proliferation in dermal papilla fibroblasts, supporting the natural hair growth cycle.

Eco-Friendly: Developed using sustainable practices, meeting consumer demand for environmentally conscious products.

Proven Efficacy

Extensive in vitro and in vivo testing has demonstrated Tricho-Solve’s effectiveness in preventing hair loss and promoting regrowth.

In Vitro Results

Tricho-Solve’s performance has been validated through rigorous laboratory testing:

• It reduced 5α-reductase gene expression by 57%, directly addressing hormonal hair loss
• IL-1α release was decreased by 51%, highlighting its anti-inflammatory capabilities
• Keratin production increased by 24%, strengthening hair fibres
• Dermal papilla fibroblast activity improved by 19%, promoting follicular health

In Vivo Results

In a 90-day clinical study with male and female participants, Tricho-Solve showed remarkable results:

• Hair density increased by 26.71%, resulting in visibly fuller hair
• Hair growth rate improved by 30.22%, reflecting healthier follicular activity
• The proportion of hairs in the anagen (growth) phase increased by 30.49%, demonstrating longer-lasting growth cycles

These results clearly establish Tricho-Solve as a powerful tool for tackling hair loss, offering visible, measurable improvements for consumers.

Formulating with Tricho-Solve

Tricho-Solve is suitable for a wide range of haircare products, from shampoos and conditioners to scalp serums and leave-in treatments. Its natural origin and advanced delivery system make it easy to integrate into formulations targeting premium and science-backed claims. Key considerations include:

• Compatibility: Works well with other actives to create multi-functional formulations.
• Applications: Ideal for scalp treatments, anti-hair loss shampoos, and densifying conditioners.
• Consumer Appeal: Aligns with trends in sustainability and natural-based solutions.

Get in Touch

Contact HARKE UK & Ireland today to speak with our technical team about incorporating Tricho-Solve into your products, or to discuss your next haircare formulation. We’d love to hear from you.

As another SCS Formulate draws to a close, we’re taking a moment to reflect on an inspiring two days packed with innovation, collaboration, and plenty of meaningful conversations. Here are the highlights from HARKE UK’s experience at this year’s event.

A Stand That Brought Sustainability to Life

This year, our stand came to life—quite literally—with the addition of over 700 live plants. More than just a decorative touch, these plants reflected our commitment to sustainability and the pending regulations regarding deforestation. Post-event, every single plant is being returned to a nursery where it will be reused, underscoring our dedication to reducing waste and embracing eco-friendly practices in everything we do.

Key Trends Shaping the Future of Personal Care

SCS Formulate is always a fantastic barometer for emerging trends, and 2024 was no exception. These were our top three trends driving discussions this year:

• Waterless Formulations: With a focus on reducing water usage in beauty and personal care, waterless products are taking centre stage as a practical and sustainable solution.
• Extremophiles: Ingredients derived from organisms that thrive in extreme conditions, showcasing their resilience and potential in high-performance formulations.
• Fermented Ingredients: The power of fermentation continues to transform personal care, offering enhanced benefits, natural appeal, and an alignment with green beauty principles.

A Spotlight on Inspiring Talks

At this year’s SCS Formulate, we were thrilled to take the stage alongside Sinerga, as well as support two of our other principals who delivered insightful presentations. These talks highlighted cutting-edge advancements in personal care, showcasing the innovative spirit that defines HARKE UK and our partners. Here’s a recap:

• The Power of Fermentation: Unlocking Enhanced Efficacy in Cosmetic Formulations – Presented by HARKE UK & Sinerga

Together with Sinerga, we explored how fermentation is revolutionising cosmetic formulations, delving into the rise of fermentation as a key trend in the industry. Our session highlighted the numerous benefits of incorporating fermented ingredients into new formulations. We also showcased Sinerga’s standout fermented ingredient, Amino Keratin (INCI: Keratin Amino Acids) for hair care, demonstrating their innovative applications and potential to transform formulations.

• High-Performance Natural Solutions: Mild for Consumers, Good for the Planet, Kind for Formulators – Presented by Syensqo

Syensqo delivered an inspiring talk on sustainable innovation, showcasing natural solutions that are gentle on consumers, environmentally responsible, and easy to formulate.

• High Natural-oil Content? High Pearl? High Attribute Expectations? Verdant’s Surfactant Solutions Stabilise Additives in Cleansing Products – Presented by Verdant

Verdant shared their expertise in surfactant innovation, demonstrating how their solutions can stabilise complex additives and meet the high-performance demands of modern personal care products.

Let’s Keep the Conversation Going

Meeting so many passionate people across the industry was truly a highlight for us. Whether you stopped by our stand, attended a talk, or simply shared insights, we loved connecting with you.

If you’re interested in exploring our catalogue of ingredients or would like some technical support with your next formulation, we’d love to hear from you. Reach out to us today and let’s collaborate!

This annual conference, run by the Society of Cosmetic Scientists, is a key event for the industry, offering delegates the opportunity to network with fellow professionals, learn from industry experts and see what new innovations and products are coming to the market in the year ahead.

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