The skincare industry continues to evolve with ingredients that deliver genuine regenerative benefits, and Uniproma’s PDRN range is capturing attention across the UK and Ireland market. From the salmon-derived PromaCare-PDRN to the newly launched vegan recombinant RJMPDRN® REC, these ingredients are helping formulators create high-performance skincare products that address multiple skin concerns.
What is PromaCare-PDRN?
PromaCare-PDRN is a purified polydeoxyribonucleotide (sodium DNA) ingredient that works at a cellular level to support natural skin regeneration processes. Extracted from salmon milt through a rigorous purification process, PDRN boasts 98% structural homology with human DNA, which is key to its exceptional compatibility and efficacy in skincare applications.
The ingredient functions by stimulating fibroblast growth and activating A2A adenosine receptors. This activation triggers the release of key growth factors including EGF, FGF, IGF and VEGF. The result is a cascade of beneficial effects that support skin health and appearance.
Key Benefits for Formulation
PromaCare-PDRN brings several proven advantages to personal care formulations including effectiveness for anti-aging applications, helping improve skin elasticity and firmness and accelerating wound healing and skin repair. It also provides UV protection benefits while offering anti-inflammatory and brightening effects.
Applications
The versatility of PromaCare-PDRN makes it suitable for various skincare categories:
- Anti-aging creams and serums targeting wrinkles and loss of firmness
- Repair-focused treatments for damaged or sensitive skin
- Acne care products that support healing and reduce inflammation
- Medical-aesthetic skincare for post-procedure recovery
- Brightening formulations that address uneven skin tone
Product Specifications
PromaCare-PDRN is available in multiple formats to suit different formulation needs:
| Product | Format | Concentration | Efficacy | Recommended Dosage |
| PDRN-P | White or light yellow powder solid | – | Anti-inflammatory repair | 0.01–2% |
| PDRN-10000L | Liquid (polyol system) | 10,000ppm | Anti-inflammatory repair | 0.01–2% |
| PDRN-5000L | Liquid (polyol system) | 5,000ppm | Anti-inflammatory repair | 0.01–2% |
RJMPDRN® REC: Vegan Recombinant PDRN
For brands looking to deliver the regenerative power of PDRN without any animal-derived ingredients, Uniproma has developed RJMPDRN® REC, a patented vegan recombinant PDRN produced via biotechnology rather than salmon milt extraction.
Like PromaCare-PDRN, RJMPDRN® REC works via A2A receptor activation, delivering potent anti-inflammatory activity through inhibition of TNF-α. It is produced through biological synthesis with 100% sequence accuracy and no batch variation, delivering consistent, high-purity results without animal sources or ocean waste.
In vivo testing over 28 days demonstrated visible wrinkle reduction across multiple parameters, as well as significant improvements in skin elasticity and firmness, enhanced barrier function and reduced erythema:
- Wrinkle Count −46.67%
- Wrinkle Area −7.44%
- Wrinkle Length −11.44%
- Skin Elasticity (R2) +30.11%
- Skin Firmness (F4) −19.83%
- Skin Barrier Function (TEWL) −17.37%
- Skin Redness (EI) −12.40%
So if you’re targeting vegan consumers or looking to reduce your reliance on marine-derived ingredients, RJMPDRN® REC could be the ideal solution.
Ready to Formulate with PDRN?
HARKE UK & Ireland supplies PromaCare-PDRN and RJMPDRN® REC across the UK and Ireland. Whether you need technical data sheets, formulation support or samples to trial, our team is here to help you bring innovative skincare solutions to market.
Contact HARKE UK & Ireland today to discuss how these two PDRN ingredients can enhance your next formulation.
