Cerafy™ Mix Repair is a breakthrough ingredient from Syensqo with powerful skin barrier repair capabilities. Formulators can now use Cerafy™ Mix Repair to deliver remarkable hydration, protection, and soothing effects, transforming their personal care formulations.
Ceramides are essential lipids naturally found in the skin’s outermost layer, the stratum corneum. They are crucial for moisture retention, protection against external aggressors and overall skin health. Their levels naturally diminish due to aging, environmental stress, and various skin conditions, leaving skin vulnerable to dryness and irritation.
Syensqo uses an innovative manufacturing process to create the Cerafy™ range, beginning with ceramide precursor extraction through yeast fermentation, followed by acylation with fatty acid. This makes Cerafy™ solutions identical to those naturally found in human skin, ensuring high bioaffinity and effectiveness in repairing the skin barrier.
About Cerafy™ Mix Repair
INCI: Water, Ceramide NP, Ceramide AP, Phytosphingosine, 2,3-Butanediol, Glyceryl Monostearate, Sodium Lauroyl Lactylate, Xanthan Gum
Cerafy™ Mix Repair is a lipids concentrate combining ceramides (NPo, NPs (3), AP (6)) and a ceramide precursor (Phytosphingosine). This unique composition is specifically engineered to reinforce the skin barrier, enhance hydration, and improve overall skin resilience. It is a versatile, water-soluble, and cold-processable ingredient, ideal for various personal care products.
Key Benefits
- 100% natural and sustainably derived through bio-fermentation
- Mimics natural skin lipids, promoting bioaffinity
- Enhances skin hydration significantly
- Repairs and reinforces the skin barrier
- Demonstrates strong soothing and anti-inflammatory properties
- Proven antioxidant activity equivalent to Vitamin E
- Easy-to-use, cold-processable, water-soluble formula
- COSMOS-approved, with a Natural Origin Index of 1.0 (ISO 16128-2)
Proven Efficacy: Testing Data Highlights
In vitro tests using EpiKutis® Skin Epiderm Model have demonstrated impressive results, using a 1% concentration of Cerafy™ Mix Repair vs. untreated skin:
- Skin Hydration: Increased skin water content by 145.7%, equivalent to a 20% glycerin solution (positive control)
- Barrier Strength: Enhanced epidermal thickness by 16%, significantly improving skin barrier integrity
- Moisture Transport: Increased Aquaporin 3 (AQP3) expression by 43%, improving water transportation within the epidermis
- Inflammation Reduction: Reduced inflammation markers (TNF-α by 30.8%, IL-1α by 9%), offering powerful soothing benefits
- Antioxidant Protection: Achieved a 59.3% reduction in Reactive Oxygen Species (ROS), offering antioxidant protection equivalent to Vitamin E (positive control)
Clinical in vivo studies also demonstrate Cerafy™ Mix Repair’s effectiveness, showing:
- Improved skin hydration by over 35% after two weeks
- Reduced transepidermal water loss (TEWL) by 22%
- Significantly diminished skin redness and sensitivity
Please get in touch to request full testing data, we’d be happy to share more details.
Applications
Cerafy™ Mix Repair is perfect for formulating high-performance products across several categories, including:
- Facial skincare (lotions, creams, serums)
- Body care products
- Cleansing oils and cleansers
- Makeup formulations
- Sunscreen products
- Hair and scalp care solutions
Formulate with Cerafy™ Mix Repair
Interested in exploring how Cerafy™ Mix Repair can elevate your formulations? Contact HARKE UK & Ireland today to learn more, see more testing data, or request a sample.
